Compare
Aubagio vs. Tysabri

Teriflunomide (Aubagio) helps treat relapsing forms of multiple sclerosis (MS) in adults. It's a type of disease-modifying therapy (DMT) that helps slow down MS and lower the number of relapses. The typical dose is 1 tablet by mouth once a day. Side effects includes headache, diarrhea, and hair loss. Teriflunomide (Aubagio) comes as a brand-name and generic medication.

• Relapsing forms of multiple sclerosis (MS)

• Headache (up to 18%)
• Higher liver enzyme levels (up to 15%)
• Diarrhea (up to 14%)
• Hair loss (up to 13%)
• Nausea (up to 11%)

• Liver problems
• Harm to an unborn baby
• Special instructions to remove teriflunomide (Aubagio) from the body quickly
• Risk of serious infections
• Serious skin reactions
• Severe allergic reactions
• Nerve problems
• Lung problems

Tysabri (natalizumab) treats relapsing forms of multiple sclerosis (MS) and moderate-to-severe Crohn's disease (CD) in adults. This medication is a monoclonal antibody that works as an integrin antagonist. It lowers the immune system's activity and lessens inflammation. Tysabri (natalizumab) is given by a healthcare professional as a once-monthly infusion through the vein (IV). Common side effects include headache and fatigue. Because of the risk for serious infection, your care team will help you enroll in the TOUCH Prescribing Program and review the medication's warnings before treatment starts.

• Relapsing forms of multiple sclerosis (MS)
• Moderate-to-severe Crohn's disease (CD) when other treatments haven't worked well

• Headache (38%)
• Fatigue or feeling extremely tired (27%)
• Urinary tract infection (21%)
• Joint pain (19%)
• Depression (19%)
• Lower respiratory tract infection (17%)
• Pain in arm or leg (16%)
• Rash or other skin irritation (up to 12%)

• Progressive multifocal leukoencephalopathy (PML)
• Other infections
• Liver problems
• Allergic reaction or infusion reaction
• Low platelet levels