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Dhivy vs. Rytary

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Dhivy

(carbidopa / levodopa)

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Rytary

(carbidopa / levodopa)

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Summary for Dhivy

Prescription only

Dhivy (carbidopa / levodopa) is FDA approved to treat adults with Parkinson's disease (PD). It can also treat conditions that cause PD symptoms. This medication raises the dopamine levels in the brain to help with PD symptoms like tremors and slowed movement. It comes as a tablet and is taken by mouth multiple times per day. The tablet has grooves (score lines) that make it easy to break for dosing and for people with trouble swallowing. Side effects include movement problems, nausea, and hallucinations.

Indications for Dhivy

Pros and Cons for Dhivy

Pros

  • Tablets can be broken into smaller pieces if needed (for your specific dose or easier swallowing)
  • First-choice option for treating PD symptoms
  • Might work within 1 hour

Cons

  • Often need to take several times per day to manage PD symptoms
  • Can make you very sleepy and possibly sudden sleep episodes
  • Can darken the color of your saliva, sweat, and urine

Common Side Effects for Dhivy

Warnings for Dhivy

  • Sleepiness or falling asleep during activities
  • High fevers and confusion when lowering the dose or stopping too suddenly
  • Hallucinations and changes in behavior and thoughts
  • Difficulty controlling impulsive behavior
  • Risk of depression and thoughts of suicide
  • Low vitamin B6 levels and seizures
  • Caution use in people with a history of heart attack and arrhythmia
  • Caution use in people with a history of stomach ulcers
  • Higher eye pressure in people with glaucoma

Summary for Rytary

Prescription only

Rytary (carbidopa / levodopa) is a combination medication that helps treat adults with symptoms of Parkinson's disease (PD). It raises the dopamine levels in the brain to improve symptoms like stiff muscles and slowed movement. Rytary (carbidopa / levodopa) is an extended-release capsule. The typical dosage is taken by mouth three times a day. Common side effects include nausea, headache, and dizziness.

Indications for Rytary

Pros and Cons for Rytary

Pros

  • Can provide more "on" time and less "off" time than immediate-release carbidopa/levodopa in people with advanced PD
  • Available in 4 different strengths
  • Can open capsule and sprinkle contents onto applesauce if you have trouble swallowing pills whole

Cons

  • Usually need to take multiple times per day
  • Can make you very sleepy and cause you to fall asleep suddenly
  • Interacts with certain monoamine oxidase inhibitors (MAOIs) and iron

Common Side Effects for Rytary

  • Nausea (up to 20%)
  • Dizziness (up to 19%)
  • Headache (up to 17%)
  • Trouble sleeping (up to 9%)
  • Dry mouth (up to 7%)
  • Unusual dreams (up to 6%)
  • Constipation (up to 6%)
  • Involuntary movements (dyskinesia, up to 5%)
  • Anxiety (up to 5%)
  • Vomiting (up to 5%)
  • Drop in blood pressure when you get up (up to 5%)

Warnings for Rytary

  • Sleepiness or falling asleep during activities
  • High fevers and confusion with treatment changes
  • Heart problems
  • Hallucinations and changes in behavior and thoughts
  • Difficulty controlling impulsive behavior
  • Low vitamin B6 levels and seizures
  • Stomach bleeding in people who've had a stomach ulcer
  • Rise in eye pressure in people with glaucoma

Prices with our coupons for Dhivy vs. Rytary

Price Card Drug Icon
Dhivy90 tablets / 25mg/100mg
$130.14-
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Carbidopa/Levodopa ER90 capsules / 48.75mg/195mg
$278.93$353.84
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